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   Cardiac functionality from cardiac acoustics

    Guy Amit

     We revisit the problem of quantitative analysis of mechanical vibro-acoustic heart signals using modern signal processing tools. We study the relationship between acoustic indices, extracted from the time-frequency energy distribution of S1, and reference echocardiographic indices that are related to left-ventricular systolic functionality. To achieve dynamic, yet controllable, hemodynamic conditions, we used clinical settings of a routine echocardiography pharmacological stress test. Work includes signal processing and feature extraction methods applied to the vibro-acoustic heart signal, and introduction of novel acoustic indices of systolic functionality.  We study the correlation between these indices and echocardiography-derived measures.                                         This study may be applicable to continuous non-invasive monitoring of cardiac systolic function.